Giovanni Ponti

Hereditary Micro‑Satellite Instable cancers associated with Lynch Syndrome: predictive biomarkers and novel immuno-therapeutic approaches

Hereditary breast and ovarian cancer: from genes to molecular targeted therapies

Hereditary familial tumors constitute 10-15% of all malignancies and present opportunities for the identification of therapeutic approaches against specific germline genetic defects. Hereditary breast and ovarian cancer (HBOC) syndrome, which is linked to the pathogenic mutations of the breast cancer 1 (