Investigator

Calogero Casà

Radiation Oncologist · Fatebenefratelli Isola Tiberina - Gemelli Isola, U.O.C. di Radioterapia Oncologica

About

Research Interests

CCCalogero Casà
Papers(1)
Assessment of Sexual …
Collaborators(8)
Gabriella MacchiaLuca TagliaferriMartina FerioliRoberto IezziRosa Pasqualina De Vi…Valentina LancellottaAngeles RovirosaBruno Fionda
Institutions(5)
Agostino Gemelli Univ…Responsible Research …University Of BolognaUniversit Cattolica D…Universitat de Barcel…

Papers

Assessment of Sexual Dysfunction in Cervical Cancer Patients after Different Treatment Modality: A Systematic Review

Background and Objectives: Cervical cancer is a leading cause of mortality among women. Chemo-radiation followed by interventional radiotherapy (IRT) is the standard of care for stage IB–IVA FIGO. Several studies have shown that image-guided adaptive IRT resulted in excellent local and pelvic control, but it is associated with vaginal toxicity and intercourse problems. The purpose of this review is to evaluate the dysfunctions of the sexual sphere in patients with cervical cancer undergoing different cervix cancer treatments. Materials and Methods: We performed a comprehensive literature search using Pub med, Scopus and Cochrane to identify all the full articles evaluating the dysfunctions of the sexual sphere. ClinicalTrials.gov was searched for ongoing or recently completed trials, and PROSPERO was searched for ongoing or recently completed systematic reviews. Results: One thousand three hundred fifty-six women included in five studies published from 2016 to 2022 were analyzed. The median age was 50 years (range 46–56 years). The median follow-up was 12 months (range 0–60). Cervical cancer diagnosis and treatment (radiotherapy, chemotherapy and surgery) negatively affected sexual intercourse. Sexual symptoms such as fibrosis, strictures, decreased elasticity and depth and mucosal atrophy promote sexual dysfunction by causing frigidity, lack of lubrication, arousal, orgasm and libido and dyspareunia. Conclusions: Physical, physiological and social factors all contribute to the modification of the sexual sphere. Cervical cancer survivors who were irradiated have lower sexual and vaginal function than the normal population. Although there are cures for reducing discomfort, effective communication about sexual dysfunctions following treatment is essential.

47Works
1Papers
8Collaborators
NeoplasmsUterine Cervical NeoplasmsSkin Neoplasms

Positions

2022–

Radiation Oncologist

Fatebenefratelli Isola Tiberina - Gemelli Isola · U.O.C. di Radioterapia Oncologica

2020–

Radiation Oncologist

Fondazione Policlinico Universitario A. Gemelli IRCCS · Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia

2016–

Resident MD

Università Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia · Gemelli Advanced Radiation Therapy

2015–

Faculty Tutor

Università Cattolica del Sacro Cuore

Education

2022

Master in Interventional Oncology

Università Cattolica del Sacro Cuore - Campus di Roma

2020

Radiation oncologist

Università Cattolica del Sacro Cuore Sede di Roma · Gemelli ART

2015

MD

Università Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia

Keywords
RadiomicsArtificial IntelligenceDigital healthInterventional RadiotherapyData miningProcess miningHuman-guided oncology