Balasubramanian Venkitaraman

Salvage cytoreductive surgery and HIPEC in chemoresistant juvenile granulosa cell tumour

Juvenile granulosa cell tumours (JGCTs) are rare ovarian neoplasms with aggressive potential and limited responsiveness to chemotherapy. We present a case of a female in early adolescence with chemoresistant JGCT and extensive peritoneal recurrence following initial surgery and systemic therapy. The patient underwent cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC) with cisplatin, resulting in a favourable postoperative course. This report highlights the role of aggressive surgical management combined with HIPEC as a promising approach for selected cases of chemoresistant peritoneal JGCT. Further studies are needed to establish standardised treatment protocols.