This work was funded by the European Union's Seventh Program for research, technological development, and demonstration (FP7, Agreement number 304810), the Fondation ARC pour la recherche contre le cancer, and by the Bruno and Helene Jöster Foundation. Qianqian Mao was supported by a research stipend from the Shanghai New Medical Union Hospital. High-throughput sequencing platform was supported by the grants ANR-10-EQPX-03 (Equipex) and ANR-10-INBS-09-08 (France Génomique Consortium) from the Agence Nationale de la Recherche ("Investissements d'Avenir" program), by the ITMO-Cancer Aviesan (Plan Cancer III) and by the SiRIC-Curie program (SiRIC Grant INCa-DGOS-465 and INCa-DGOSInserm_12554). Funding