This study was part of the ELEVATE consortium, which has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement no, 825747. Results of the Roche cobas 4800 assay and Next-Generation Sequence were obtained thanks to Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) funding 2018/220176, 2020/00445-6 and 2022/00712-0. Funding