Endometrial Malignancy in Breast Cancer Patients With or Without AUB

NCT05977829CompletedOBSERVATIONAL

Summary

In order to assess the hysteroscopic, histopathologic, and ultrasonographic aspects of uterine monitoring in postmenopausal breast cancer patients with or without abnormal uterine bleeding (AUB), as well as to calculate the risk of endometrial cancer in women with or without AUB.

Key Facts

Lead Sponsor

University of Campania Luigi Vanvitelli

Enrollment

283

Start Date

2020-01-01

Completion Date

2021-06-01

Study Type

OBSERVATIONAL

Official Title

Ultrasonographic, Hysteroscopic, Histopathologic Findings and Risk of Endometrial

Interventions

UltrasoundHysteroscopy

Conditions

Endometrial Neoplasms

Eligibility

Age Range

43 Years – 70 Years

Sex

FEMALE

Inclusion Criteria:

* In case of AUB: ultrasonographic endometrial thickness \>5 mm at transvaginal ultrasound
* In case of non-AUB group ultrasonographic suspicion of endometrial or myometrial abnormalities

Exclusion Criteria:

* severe comorbidities (cardiovascular, metabolic, endocrine, and immunological disorders)
* receiving any other form of pharmacologic therapy

Outcome Measures

Primary Outcomes

Endometrial cancer rate

Time frame: 1 month after admission

Endometrial hyperplasia rate

Time frame: 1 month after admission

Locations

University of Cagliari, Cagliari, Italy

Endometrial Malignancy in Breast Cancer Patients With or Without AUB