Inflammatory Index as a Predictor for Endometrial Cancer: an Observational Study

NCT05657483RecruitingOBSERVATIONAL

Summary

Key Facts

Lead Sponsor

University of Campania Luigi Vanvitelli

Enrollment

128

Start Date

2022-12-10

Completion Date

2024-12-10

Study Type

OBSERVATIONAL

Official Title

Inflammatory Index as a Predictor for Endometrial Cancer: an Observational Study

Interventions

Venous blood sampleSurgical staging of endometrial cancer

Conditions

Endometrial NeoplasmsInflammatory Response

Eligibility

Age Range

18 Years+

Sex

FEMALE

Inclusion Criteria:

* Patients histologically diagnosed with endometrial cancer.
* Patients undergoing surgical staging of the disease.
* Patients undergoing full-body CT-scan 30 days before enrollment.
* At least 18-year-old patients.

Exclusion Criteria:

* Unfit to plead.
* Patients with chronic inflammatory diseases (IBDs; rheumatic conditions).
* Synchronous tumors or cancer diagnosis in the previous 3 years.
* Patients undergoing steroid therapy in the last 30 days prior to recruitment

Outcome Measures

Primary Outcomes

Grading

Anatomic pathology report of cell anaplasia in the sampled tumor

Time frame: 30 days after surgery

Staging

Anatomic pathology report of extent to which the cancer has spread

Time frame: 30 days after surgery

Histotype

Anatomic pathology report of tissue types that arise during the growth of cancer

Time frame: 30 days after surgery

Lymphovascular space invasion

Prognostic factor for recurrence and survival in endometrial cancer

Time frame: 30 days after surgery

Molecular profile

Biomarker testing of genes and/or proteins

Time frame: 30 days after surgery

Locations

Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy