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The Role of Clean Intermittent Catheterization in Patients Undergoing Radiotherapy After Radical Hysterectomy for Cervical Cancer

NCT05410444CompletedNAINTERVENTIONAL

Summary

Through a prospective, randomized and controlled research design method, this study implemented intermittent catheterization for patients with urinary dysfunction after postoperative radiotherapy of cervical cancer, formulated a reasonable bladder rehabilitation training plan, reduced the amount of residual urine, restored bladder function as soon as possible, reduced the incidence of urinary complications and readmission rate, and improved the quality of life of patients, To comprehensively evaluate the application value of intermittent catheterization in patients with micturition dysfunction after postoperative radiotherapy for cervical cancer.

Key Facts

Lead Sponsor

Zhejiang Cancer Hospital

Enrollment

Start Date

2018-07-01

Completion Date

2020-12-01

Study Type

INTERVENTIONAL

Official Title

Application of Intermittent Catheterization in Patients With Micturition Dysfunction After Postoperative Radiotherapy for Cervical Cancer

Interventions

Clean Intermittent CatheterizationIndwelling catheterization

Conditions

Uterine Cervical Neoplasms

Eligibility

Age Range

18 Years – 65 Years

Sex

FEMALE

Inclusion Criteria:

* Older than 18 and younger than 65; ② Have normal independent judgment ability; ③ According to the staging standard of International Federation of Obstetrics and gynecology (FIGO) in 2009, the preoperative staging was stage Ⅰ A1 -Ⅱ A2; ④ Patients who need postoperative radiotherapy according to the provisions of NCCN clinical practice guide for cervical cancer in 2015; ⑤ Residual urine volume is more than 100ml.

Exclusion Criteria:

① Extensive hysterectomy with bladder repair; ② Urinary tract infection has occurred at the time of admission / transfer; ③ Hydronephrosis; ④ Patients with contraindications to intermittent catheterization; ⑤ Do not agree to participate in this clinical study; ⑥ Patients with communication difficulties. -

Outcome Measures

Primary Outcomes

the recovery rate of bladder function

At the end of radiotherapy, the recovery rate of bladder function in the observation group was higher than that in the control group (P \< 0.05)

Time frame: 3 years

Secondary Outcomes

the incidence of urinary tract infection

During the radiotherapy, the incidence of urinary tract infection in the observation group was significantly less than that in the control group (P = 0).

Time frame: 3 years

the bladder volume

At the end of radiotherapy, the bladder volume of the two groups decreased compared with that before radiotherapy. However, there was no significant difference between two groups (P \> 0.05).

Time frame: 3 years

Locations

Zhejiang Cancer Hospital, Hangzhou, China

Linked Diseases

Uterine Cervical Neoplasms

Uterine Cervical Neoplasms — a type of gynecological cancer.