Where does OCRA's clinical trial data come from?

OCRA indexes clinical trials from ClinicalTrials.gov, the official U.S. registry maintained by the National Library of Medicine. Trials are matched to diseases, investigators, and funded research tracked across the platform.

How do I find clinical trials for ovarian cancer?

Search by condition, treatment type, trial phase, or NCT identifier. Each trial page shows current status, eligibility criteria, study locations, and a direct link to the ClinicalTrials.gov source record.

How often is clinical trial data updated?

Trial data is refreshed through periodic ingestion from the ClinicalTrials.gov v2 API. Status changes, new enrollments, and newly registered trials are captured during each update cycle.

Promoting Cervical Cancer Screening Through the Advocacy of Screened Women

NCT04960748CompletedPHASE2INTERVENTIONAL

Summary

This study pilots a 7-session group intervention among 40 screened women, 20 of whom will be randomly assigned to take part in the intervention, and 20 to the wait-list control. Assessments will be administered at baseline and month 6 to index participants as well as up to three unscreened female social network members of each index participant (up to 120 total). The primary outcome is CC screening among participating social network members.

Key Facts

Lead Sponsor

RAND

Enrollment

143

Start Date

2021-08-30

Completion Date

2022-04-25

Study Type

INTERVENTIONAL

Official Title

Pilot of a Network-driven, Advocacy Intervention to Promote Cervical Cancer Screening in Uganda

Interventions

WOMEN FIGHTING TO STOP CERVICAL CANCER

Conditions

Cervical Cancer Prevention

Eligibility

Age Range

18 Years+

Sex

FEMALE

Inclusion Criteria:

* age 18 years or older
* has been previously screened for cervical cancer
* has told at least one woman in her social network about her cervical cancer screening experience

Exclusion Criteria:

* unstable medical status (e.g., advance disease stage that calls into question her ability to complete the 6-month study)

Outcome Measures

Primary Outcomes

Proportion of social network members who report cervical cancer screening

cervical cancer screening among women in social network

Time frame: past 6 months

Secondary Outcomes

Proportion of index participants who self-report engagement in cervical cancer (CC) prevention advocacy

discussing cervical cancer and encouraging CC screening with women in social network

Time frame: past 6 months

Locations

Buyinja HCIV, Namayingo, Uganda

Linked Papers

2023-09-01

Increased Knowledge Mediates the Effect of Game Changers for Cervical Cancer Prevention on Diffusion of Cervical Cancer Screening Advocacy Among Social Network Members in a Pilot Trial

Abstract Background Game Changers for Cervical Cancer Prevention (GC-CCP), a peer-led, group advocacy training intervention, increased cervical cancer (CC) prevention advocacy not only among intervention recipients, but also their social network members (referred to as “alters”) who were targeted with advocacy in a pilot randomized controlled trial. We examined mediators and moderators of this effect on alter advocacy, to understand how and for whom the intervention had such an effect. Method Forty women (index participants) who had recently screened for CC enrolled and were randomly assigned to receive the GC-CCP intervention (n = 20) or the wait-list control (n = 20). Up to three alters from each participant (n = 103) were surveyed at baseline and month 6. Measures of CC-related cognitive constructs (knowledge, enacted stigma, and risk management self-efficacy), as well as extent of advocacy received from index participants, were assessed as mediators of the intervention effect on alter advocacy using multivariate regression analyses. Alter characteristics were examined as moderators. Results Increased CC-related knowledge partially mediated the intervention effect on increased alter engagement in CC prevention advocacy; those with greater gains in knowledge reported greater engagement in advocacy. No moderators of the intervention effect were identified. Conclusion The effect of GC-CCP on alter CC prevention advocacy is enhanced by increased alter knowledge pertaining to CC prevention, causes, and treatment and suggests this may be key for diffusion of intervention effects on increased CC prevention advocacy throughout a social network. Trial Registration NCT04960748 (registered on clinicaltrials.gov, 7/14/2021).

Linked Investigators

Ishita Ghai