An In-vitro Real-time System Based on Tissue Smears to Identify Malignancy During Hysteroscopic Procedure

NCT03971032UNKNOWNNAINTERVENTIONAL

Summary

The aim of the current study is to develop a near real-time system using infrared spectroscopy, that will evaluate the histological specimen that was removed from the uterine cavity during the hysteroscopy.

Key Facts

Lead Sponsor

Hillel Yaffe Medical Center

Enrollment

300

Start Date

2019-12-31

Completion Date

2021-05-01

Study Type

INTERVENTIONAL

Official Title

A Development of an In-vitro Real-time System Based on Tissue Smears to Identify Malignancy During Hysteroscopic Procedure Using FTIR-ATR Spectroscopy

Interventions

HysteroscopyInfrared Spectroscopy

Conditions

Uterine Cervical NeoplasmUterine Neoplasms

Eligibility

Age Range

18 Years+

Sex

FEMALE

Inclusion Criteria:

* Patients undergoing hysteroscopy

Exclusion Criteria:

* Pregnancy

Outcome Measures

Primary Outcomes

Comparison of infrared spectroscopy with routine histopathology

Tissue smears that have undergone infrared spectroscopy during hysteroscopy will have a different spectral absorption than healthy tissue, thus indicating malignancy. These results will be compared to the results of routine histopathology to determine accuracy of spectroscopy to indicate malignancy.

Time frame: 3 years

Locations

Hillel Yaffe Medical Center, Hadera, Israel

Linked Diseases

Uterine Neoplasms

Uterine Neoplasms — a type of gynecological cancer.

An In-vitro Real-time System Based on Tissue Smears to Identify Malignancy During Hysteroscopic Procedure