Correlation Between Hysteroscopic Diagnosis of Endometrial Hyperplasia and Histopathological Examination

Summary

A prospective cohort study at a Tertiary University Hospital. From January to December 2018, we enrolled women with the following criteria: abnormal uterine bleeding in post-menopause, endometrial thickening in pre-or post-menopause; tamoxifen usage. Patients underwent office hysteroscopy with a 5-mm continuous-flow hysteroscope and endometrial biopsies were taken using miniaturized instruments. Senior operators had to foresee histopathological diagnosis using a questionnaire. Histopathological examination was conducted to confirm the diagnosis.

Key Facts

Interventions

Conditions

Eligibility

Inclusion Criteria:

* abnormal uterine bleeding in post-menopause
* ultrasonographic detection of endometrial thickening in pre-menopause
* ultrasonographic detection of endometrial thickening in post-menopause
* follow-up after Tamoxifen-based therapy regimens

Exclusion Criteria:

* severe urinary symptoms
* history of severe comorbidities (autoimmune disorders, chronic diseases and severe cardiac disease)

Outcome Measures

Locations