Summary
Background: * Monocytes are a type of white blood cell found in human blood. They help the immune system. Researchers have found that monocytes taken from the blood of healthy people can kill tumor cells. Now they want to know if monocytes taken from the blood of people with ovarian cancer can kill tumor cells. * In addition, native host anti-tumor cell mediated immune mechanisms may play a role in clinical outcome of epithelial ovarian cancer; data indicate that the presence of intra-tumoral CD3+ T-cells was shown to prognosticate improved outcome in advanced ovarian cancer. Furthermore, non-cellular components in the blood, such as exosomes, may influence outcome. Objective: \- To see if monocytes taken from the blood of people with ovarian cancer can kill tumor cells. Eligibility: \- Women 18 years and older with ovarian cancer. Design: * Participants will be screened with: * Medical history and physical exam. * Blood tests. * CT scan of the chest, abdomen, and pelvis and/or an MRI. For these scans, they will lie in a machine that takes pictures of their body. * A small amount of blood (two tubes) will be collected by needle during one visit.
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* INCLUSION CRITERIA * Females greater than or equal to 18 years of age with histologically proven ovarian, primary peritoneal or fallopian tube cancer. * Currently not on therapy. Must be at least 2 weeks from prior therapy. * Ability and willingness to provide informed consent to participation. EXCLUSION CRITERIA \- Children are not eligible.