Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants

Summary

RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer. PURPOSE: This laboratory study is looking at an assay in determining cancer resistance in patients with metastatic cancer and in healthy participants.

Key Facts

Interventions

Conditions

Eligibility

Inclusion Criteria:

-Meets 1 of the following criteria:

* Diagnosis of metastatic cancer including, but not limited to, any of the following:

  * Stage IV non-small cell lung cancer
  * Extensive-stage small cell lung cancer
  * Metastatic testicular cancer
  * Stage IV breast carcinoma
  * Stage III or IV ovarian carcinoma
  * Stage IV endometrial carcinoma
  * Stage IV prostate carcinoma
  * Stage IV colorectal or pancreatic cancer
  * Stage IV renal cancer
  * Stage III or IV non-Hodgkin's lymphoma
  * Stage IV bladder cancer
  * Stage III multiple myeloma (Salmon-Durie staging)
  * Metastatic melanoma
  * Metastatic sarcoma
* Healthy participant, meeting the following criteria:

  * No prior cancer
  * Over 50 years of age

Exclusion Criteria:

* Serious medical or psychiatric condition that would preclude study compliance
* Chemotherapy or radiotherapy within the past 3 months (patient)
* Prior immunosuppressive therapy or radiotherapy for any disease (healthy participant)

Outcome Measures

Locations