Contrast-Enhanced Ultrasonography in Diagnosing Early-Stage Ovarian Cancer in Patients With an Adnexal Mass Undergoing Surgery to Remove the Ovary

Summary

RATIONALE: New diagnostic procedures, such as contrast-enhanced ultrasonography, may be an effective method of finding ovarian cancer. PURPOSE: This clinical trial is studying how well contrast-enhanced ultrasonography works in diagnosing early-stage ovarian cancer in patients with an adnexal mass undergoing surgery to remove the ovary.

Key Facts

Interventions

Conditions

Eligibility

DISEASE CHARACTERISTICS:

* Diagnosis of adnexal mass
* Scheduled to undergo surgical oophorectomy

PATIENT CHARACTERISTICS:

* Not pregnant or nursing
* Negative pregnancy test
* No known respiratory failure as manifested by signs and symptoms of carbon dioxide retention or hypoxemia
* No pulmonary vasculitis
* No known history of severe emphysema
* No known history of pulmonary emboli
* No other condition that causes pulmonary hypertension due to compromised pulmonary arterial vasculature
* No known history of severe pulmonary hypertension (i.e., systolic pulmonary artery pressures \> 90 mm Hg)
* No known history of congenital heart defect that creates a bidirectional or right-to-left shunt
* No worsening or clinically unstable congestive heart failure
* No known acute myocardial infarction or acute coronary syndromes
* No known serious ventricular arrhythmias
* Not at high risk for arrhythmia due to prolongation of the QT interval
* No known or suspected hypersensitivity to blood, blood products, or albumin
* No known hypersensitivity to perflutren
* No known or suspected hypersensitivity to octafluoropropane or any other ingredients of perflutren lipid microspheres (Definity®)
* No mental status problems, illiteracy, or other circumstance that would preclude giving informed consent

PRIOR CONCURRENT THERAPY:

* See Disease Characteristics

Outcome Measures

Locations