The aim of this study is to visualize the tumor hypoxic tissue, the potential quantitative changes and the biological behavior of cervical carcinoma (primary and / or lymph nodes) before, during and after radiochemotherapy with the novel hypoxia PET tracer 18FAZA.
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Inclusion Criteria: * First diagnosis of histologically proven cervical cancer FIGO stage IB2 to IVA. * Treatment intention for the purpose of achieving cure * Age \< 80 years * No previous standard or radical hysterectomy Exclusion Criteria: * Pregnancy, breast-feeding women, patients that are not able to lie motionless for one hour.Palliative treatment, recurrent disease, neoadjuvant chemotherapy, other pre-existing malignancies, age \> 80 years,