Summary
Doctors will take some tissue from the tissue removed during surgery in order to study how the blood vessels of the tumor respond to radiation therapy. The tissue obtained will be used to determine how these tumor blood vessels respond to radiation therapy delivered to the tumor, after it has been removed. This radiation is delivered in the research lab. This research is being conducted in order to develop new methods to treat tumors by radiation therapy. No additional surgery will be performed to obtain these samples, and only materials that remain after all diagnostic testing has been completed will be used.
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Inclusion Criteria: * Patients who are felt to have adequate tumor volume for these studies, at least a 2 x 2 x 2 cm3 tumor by physical exam, imaging studies or colonoscopy reports * Primary or recurrent tumors are eligible * Patients must be suitable candidates for surgery * Patients who have signed the informed consent Exclusion Criteria: * Patients who are not considered suitable candidates for surgery * Patients who have received prior radiation therapy to the tumor being removed * Patients who have received chemotherapy within 6 months of tumor removal * Patients who are pregnant * Patients may choose to be excluded at any time * Minors are excluded from this study because there are expected to be very few minors with the tumor types which the investigators are evaluating in this study